Drug Designing: Open Access
Open Access

Department of Internal Medicine, Linxiang Zhongya Hospital, Yueyang 414300, China

Publications

• Research Article   
  Qi and Blood Deficiency Contributes to Peripheral T-Cell Dysfunction and Reduced Natural Killer Cell Activity in Gastric Cancer
  Author(s): Zeyong Xie*
  
  Gastric Cancer (GC), a major cause of cancer-related mortality, is susceptible to invasion and metastasis, which triggers dismal prognosis. Traditional Chinese medicine (TCM) exerts a pivotal role in various cancers, including GC. Correct syndrome differentiation is the most important principle guiding the treatment strategy. Here in, the present study aims to explore the relationship of different TCM syndrome types of GC patients and the cellular immune function, which was evaluated by observing peripheral T-cell subsets and activity of Natural Killer (NK) cells. GC patients and healthy controls were enrolled in this study, with venous blood during fasting collected. Patients with deficiency syndromes exhibited decreased number of CD4+ T-cells, ratio of CD4+/CD8+ T-cells and the activity of NK cells as compared with those with sufficiency syndromes. Then, the rel.. View More»
  DOI: 10.35248/2169-0138.21.10.180

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