Journal of Hepatology and Gastrointestinal disorders

Journal of Hepatology and Gastrointestinal disorders
Open Access

ISSN: 2475-3181

Weiqian Sun

Department of Nephrology, Shanghai Gumei Community Health Service Center, 201100, Shanghai, China

  • Research Article   
    Guben Xiezhuo Recipe Alleviated Colon Dialysis on Urotoxin-Induced Intestinal Barrier Injury and Systemic Inflammation
    Author(s): Haidong He*, Hongmei Huan, Yuyan Tang, Hongru Wang, Weiqian Sun and Xudong Xu

    Background: Chronic Kidney Disease (CKD) is a major disease that endangers public health around the world. The urinary toxins produced in the disease can induce intestinal barrier damage and systemic inflammation, which further aggravates the disease and creates a vicious circle. Therefore, this work carried out cell-level research to determine the ability of Guben Xiezhuo Recipe for colon dialysis to repair the intestinal barrier and to interfere with the entire process. Methods: T84 cells were divided into six groups, one of which was a control group, and the experimental components were divided into five groups according to the level of urinary toxin content and the different drugs added. Perform a series of tests on six groups. Immunofluorescence technique was used to analyze the expression characteristics of intestinal epithelial tight .. View More»
    DOI: 10.35248/2475-3181.1000199

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