ISSN: 2684-1266
Department of Medicine, "Titu Maiorescu" University, Bucharest, Romania
Dr. Brasoveanu Vladislav is a primary surgeon, head of the Liver Transplant Section "Dan Setlacec" of the Fundeni Clinical Institute, Bucharest. Dr. Vlad Brasoveanu started working with Prof. Irinel Popescu in 1996, being one of his first students. Dr. Brasoveanu Vladislav has the following medical skills:
Competence in Oncological Surgery
Competence in Laparoscopic Surgery
Competence in Hepato-Bilio-Pancreatic Surgery
 Research   
								
																The Immune Response in Gastrointestinal Stromal Tumors 
																Author(s): Vlad Herlea*, Alexandra Rosulescu, Andreea Iorgescu, Simona Olimpia Dima, Traian Dumitrascu, Vladislav Brasoveanu, Cezar Stroescu, Catalin Vasilescu and Irinel Popescu             
								
																
						 Background: Gastrointestinal stromal tumors (GISTs) are the most frequent tumors with mesenchymal origin at the
  level of the digestive tract. Assessment of intratumoral immune cells can provide valuable prognostic information
  and may contribute to the development of targeted immune therapies for selected cases. Here in we evaluated the
  inflammatory infiltrate in gastrointestinal stromal tumors, the ratios between cytotoxic and helper T cells and their
  prognostic significance.
Methods: We retrospectively analysed 25 cases of GISTs and extragastrointestinal stromal tumors (EGISTs).
  Immunohistochemical testing for CD3, CD4, CD8, CD20 and CD68 was performed to emphasize the immune
  cells. Inflammatory cells were quantified with the help of ImageJ software. Statistical analysis was performed to
  search for correlation between the.. View More»
						  
																DOI:
								10.35248/2684-1266.20.6.125