Gynecology & Obstetrics
Open Access

Department of Molecular Medicine and Development, University of Siena, Italy

Publications

• Research Article   
  Clinical Activity of a Combination of Isoflavones, Agnus castus and Magnolia in the Menopause: A Controlled Study on Estromineral Serena Plus
  Author(s): Vincenzo De Leo* and Claudio Benvenuti
  
  Introduction: Falling oestrogen levels in the perimenopause alter the function of dopamine, melatonin and neuropeptides, and therefore affect thermoregulation, vasomotor stability, mood regulation, quality of sleep and psychological wellbeing. When Hormone Replacement Therapy (HRT) is not appropriate, taking food supplements can be useful. A new food supplement for the menopause (ESP), which contains soy isoflavones, Magnolia and Agnus castus extracts, acts on the vasomotor and psycho affective symptoms and has shown interesting preliminary clinical results. This study, with a controlled design, confirms the clinical activity of ESP in symptomatic postmenopausal women. Method: Menopausal women with more than five moderate hot flushes a day and with changes in mood or sleep were enrolled in a randomised, controlled, parallel-group, multicentr.. View More»
  DOI: 10.35248/2161-10932.20.10.528

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