Department of Human Anatomy, University of Uyo Akwa, Ibom State, Nigeria
Aloe Vera Heals Gastric Ulcer in 7 Days than Omeprazole and Cimetidine : Prostaglandin?
Author(s): Jimmy EO*, Umoh IU and Usun VJ
Peptic ulcer disease is becoming a very common disease as it is associated with lifestyle e.g eating habits more than infection, by bacteria, H. pylori . There are many treatments for the disease which are not very potent for the eradication of the disease. A comparative study was therefore carried out with Aloe Vera, cimetidine and omeprazole to arrive at the most potent treatment drug. A total of thirty (30) male and female rats were used for the study. The Aloe Vera extract with LD50 of 1870.83 mg/kg was administered in three dosages; low, medial and high, 187.08 mg/kg, 374.42 mg/kg and 561.25 mg/kg respectively in groups (3-4) while cimetidine and omeprazole in groups V and VI respectively for 28 days. Gastric HCl increased significantly p<0.1 in group 3 as compared to the control but was not signif.. View More»