Journal of Infectious Diseases & Preventive Medicine
Open Access
ISSN: 2329-8731
ISSN: 2329-8731
Department of Vaccine and Drugs Development, The National Research and Innovation Agency, Jakarta, Indonesia, Republic of Korea
Research Article
A Novel Limosilactobacillus reuteri Strain Byun-re-01 Exhibits Promising
Probiotic Properties for Further Use as Preservatives: An In Vivo and In Silico Study
Author(s): Seungchan Cho, Sung June Byun and Sukchan Lee*
Antibiotics had been a pivotal substance to be supplemented in the food for poultry flock with a main purpose to
improve their yields in order to gain profits. However, its long-term use costs some adverse effects such as resistance
and tolerance. Hence, a new platform is of urgency to figure out. We discovered that our probiotic bacteria, which
through the whole-genome sequencing was identified as Limosilactobacillus reuteri strain Byun-re-01 (L. reuteri Byun-
re-01), exhibited promising biological properties to substitute the existing use of antibiotics. Oral administration of L. reuteri Byun-re-01 was shown to provide local protection by producing anti-inflammatory cytokines mainly IFN-β
and IFN-γ in mRNA levels. In addition, they suppressed the expression of viral capsid mRNA of MNV indicating
their antiviral activity. They w.. View More»
DOI:
10.35841/2329-8731.22.10.271