Medical & Surgical Urology
Open Access
ISSN: 2168-9857
ISSN: 2168-9857
Department of Urology, Yokohama General Hospital, Japan
Research
Definitive Therapy of Early Prostate Cancer with Transurethral MicrowaveThermotherapy after Prostate Volume Reduction by Androgen Deprivation: A17-Year Experience of a Potential Alternative to Radical Surgery
Author(s): Ken Koshiba*, Hideyuki Mizoguchi, Ryuta Suzuki, Yutaka Jujo, Masahiro Aihara, Hirotaka Nakajo and Satoru Shimura
Background: Transurethral Microwave Thermotherapy (TUMT) has shown limited efficacy as a treatment for prostate cancer, mainly because of the inability of microwaves to reach the peripheral region of the prostate. Pretreatment with Androgen Deprivation Therapy (ADT) may increase TUMT efficacy by reducing the prostate size.
Objective: To examine the clinical outcomes of patients undergoing TUMT after at least 3 months of ADT. Design, setting, and participants: One hundred twenty-three men with early, non-metastatic prostate cancer and Prostate-Specific Antigen (PSA) levels of 4.0 ng/mL or higher were enrolled between 2001 and 2011 and followed up until 2017. TUMT was performed after at least 3 months of ADT and the efficacy of this treatment was confirmed by radical Transurethral Resection of the Prostate (TURP) performed at least 3 months after.. View More»
DOI:
10.35248/2168-9857.19.8.225