Immunotherapy: Open Access
Open Access
ISSN: 2471-9552
ISSN: 2471-9552
Department of Parasitology and Mycology, School of Medicine, Arak University of Medical Sciences, Arak, Iran
Review
Toxoplasma gondii Exosomes: Versatile Tools for Understanding Host-Parasite Interactions, Developing Therapeutics, and Modulating Host Immune Responses and Metabolism
Author(s): Nastaran Barati, Ehsan Ahmadpour, Reza Ghasemikhah, Salman Zafari, Eissa Soleymani and Seyedmousa Motavallihaghi*
Toxoplasma gondii (T. gondii) is an obligate intracellular parasite that can infect a wide range of animals, including humans. Exosomes are extracellular vesicles that are released by cells and have been shown to play important roles in cell-to-cell communication. Recent studies have shown that T. gondii also secretes exosomes that can modulate host immune responses and contribute to the pathogenesis of the infection. This review article will summarize the current knowledge on T. gondii exosomes and their potential implications in infection. T. gondii exosomes are a versatile and complex system that can modulate various host functions, including the immune response, microbiota, epigenome, and metabolism. They have potential diagnostic and therapeutic applications and can be used in biotechnology. However, further research is neede.. View More»
DOI:
10.35248/2471-9552.23.09.222