Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
ISSN: 2155-6148
Department of Anaesthesia, University College Hospital, Ibadan, Nigeria
Research Article
Effects of Ketofol Intravenous Anaesthesia Versus Isoflurane On Emergence Agitation in Children Undergoing Cataract Extraction
Author(s): Olayinka R Eyelade* and Olubukola S Ojediran
Objectives: Emergence agitation is a common post-operative complication in children following the use of
inhalational anesthetic agents. The study was designed to evaluate the effects of Ketofol TIVA and isoflurane on the
incidence and severity of Emergence Agitation (EA) in children who had cataract surgery.
Methods: Ninety-four patients between the ages of two and six years with American Society of Anaesthesiologist
(ASA) physical status 1 or 11 undergoing elective cataract surgery under general anesthesia were randomised into two
groups of 47 patients each. Induction of anaesthesia was with 2-3 mg/kg of propofol in both groups. One group of
patients (group A) was maintained with ketofol TIVA in the ratio of 1:10 (1 mg/kg/hr of ketamine and 10 mg/kg of
propofol) while the second group was maintained on 1-1.2 MAC of isoflura.. View More»