Journal of Hepatology and Gastrointestinal disorders

Journal of Hepatology and Gastrointestinal disorders
Open Access

ISSN: 2475-3181


Rohey Jan

Department of Anesthesiology and Critical Care Medicine, Kochi, Kerala, India

  • Research Article   
    Effect of Polyethylene Glycol vs. Lactulose in the Treatment of Overt Hepatic Encephalopathy
    Author(s): Waseem Raja*, Rohey Jan, Benoy Sebastian, Sunil K Mathai and Ashfaq

    Introduction: Hepatic Encephalopathy is one of the most common causes of hospitalization for cirrhotic patients. Lactulose has long been used as the standard therapy for the treatment of acute HE. This study evaluated the efficacy of PEG as compared with lactulose for the initial treatment of HE. Aims and Objective: (1) To compare efficacy of PEG 3350 electrolyte solution over lactulose in patients admitted for hepatic encephalopathy. (2) To determine whether treatment with PEG will reduce duration of hospital stay, and whether PEG can be an effective additional treatment option for HE. Material and methods: This prospective, randomized, comparative study was conducted in the Department of Gastroenterology Medical Trust hospital, Kochi–Kerala India, over a period of two year from May 2015–April 2017 fol.. Read More»

    Abstract PDF