ISSN: 2576-1447
Bay Hematology Oncology, 8221 Teal Drive, Suite 302, Easton, Maryland, USA
Rodrigo Erlich has been involved in many quantitative as well as qualitative studies; but her expertise are mostly related to qualitative and action research. Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Wenzhou Medical University, 306 Hualongqiao Road, Wenzhou, Zhejiang, P.R. China
Case Report
Clinical Utility of Target Selectorâ„¢ ctDNA Testing: Detection of EGFR Mutations via Liquid Biopsy Enabled Targeted Therapy Selection for Patients with Advanced NSCLC
Author(s): Veena M Singh*, Rodrigo Erlich and Cecile Rose T Vibat
Background: Molecular profiling of tumors provides information key for devising personalized therapeutic strategies for managing disease in cancer patients. A liquid biopsy is emerging as a sensitive means to evaluate biomarker status without the complications and costs associated with surgical biopsies, particularly for patients unable or unwilling to undergo invasive procedures.
Materials and Methods: Patient blood specimens were collected in Biocept’s proprietary Blood Collection Tubes for liquid biopsy testing in Biocept’s CLIA-certified, CAP-accredited laboratory. Dual Circulating Tumor Cell (CTC) and circulating tumor DNA (ctDNA) platforms were utilized to detect ALK or ROS1 gene rearrangements by FISH, or EGFR mutations, respectively.
Results: Described are three metastatic NSCLC patients for which liq.. View More»
DOI:
10.4172/2576-1447.1000113