Immunogenetics: Open Access
Open Access
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Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China
Research
No Clear Benefit to the use of Corticosteroid as Treatment in Adult Patients with Coronavirus Disease 2019: A Retrospective Cohort Study
Author(s): Yongming Liu*, Dan Wang, Juan Wang, Qunqun Jiang, Juan Yang, Jun Li, Chang Gao, Haiwei Jiang and Lintong Ge
Coronavirus disease 2019 (COVID-19) is becoming an increasing global health issue which has spread across the
globe. We aimed to study the effect of corticosteroids in the treatment of adult inpatients with COVID-19. A
retrospective cohort of 115 consecutive adult COVID-19 patients admitted to Hubei NO.3 People’s Hospital of
Jianghan University between Jan 18, 2020, and Feb 28, 2020 was analysed to study the effectiveness of corticosteroid.
They were categorized according to whether or not corticosteroid therapy was given, and compared in terms of
demographic characteristics, clinical features, laboratory indicators and clinical outcomes. The primary endpoint
was defined as either mortality or intensive care unit (ICU) admission. Known adverse prognostic factors were
used as covariates in multiple logistic regressions to adjust for their confounding effects .. View More»
DOI:
10.35248/igoa.20.5.129