Journal of Tumor Research
Open Access
ISSN: 2684-1258
ISSN: 2684-1258
Department of Biomarkers and Diagnostics Biometrics, Novartis Institute for Biomedical Research, Eas, USA
Opinion
Analysis of Circulating Tumor DNA and Its Mutations
Author(s): Quan Zou*
Rising techniques to stumble on tumor derived dna in the blood plasma of sufferers with lymphomas so known as circulating tumor DNA have the capability to change the manner wherein lymphoma is identified and managed in the sanatorium. The feasible programs for circulating tumor are severe, including mutation genotyping, response tracking, and detection of minimal residual ailment all through a time of radiographic remission. This article discusses the method for detecting circulating tumor in competitive B mobile lymphomas, which includes virtual polymerase chain response, centered sequencing of immunoglobulin receptors, and focused subsequent-technology sequencing. The benefits of each of those strategies also are as compared, with a focus on promising clinical applications. These include identification of molecular subtypes, cellular of starting place and double hit lymphomas from p.. View More»