Journal of Infectious Diseases & Preventive Medicine
Open Access
ISSN: 2329-8731
ISSN: 2329-8731
Department of Clinical Laboratory Services, Institute of Human Virology, Abuja, Nigeria
Review Article
Epidemiology, Viral Pathogenesis, Host-Immune Response and PotentialVaccine Trial for the Treatment of SARS-CoV-2 Infection
Author(s): Abbas Abel Anzaku*, Olasinbo Balogun, Akwashiki Ombugadu, Nneka Egbuchulam, Ibrahim Yusuf, Ifeanyichuku Odoh, Nurudeen Olalekan Oketade and Akpason Esla Amre
Background: The current outbreak of COVID-19 caused by SARS-CoV-2 raised fundamental public health concerns
as its emergence has been marked the third introduction of a highly pathogenic coronavirus into the human
population after SARS-CoV and MERS-CoV in the twenty-first century. Recent advancement of SARS-CoV-2
infection revealed mechanism of immune evasion during the pathogenesis. Hence, this study reviewed available
literature on epidemiology of SARS-CoV-2, viral pathogenesis, host immune response to the infection and potential
vaccine trial for the treatment of the infection.
Methods: Systematic review technique was used for this study.
Results: This study provides an immunological insight i nto the SARS-CoV-2 infection for better understating of the
virus and as well as the strategies for use in.. View More»
DOI:
10.35248/2329-8731.20.8.209