Journal of Proteomics & Bioinformatics

Journal of Proteomics & Bioinformatics
Open Access

ISSN: 0974-276X

+44 1223 790975

Myron R Szewczuk

Department of Biomedical and Molecular Sciences, Queen’s University, Quebec, Canada

  • Short Communication   
    Role of Phosphoproteomics in Protein Activity
    Author(s): Myron R Szewczuk*

    Phosphoproteomics is a branch of proteomics that searches for, catalogues, and describes proteins with phosphate groups as a posttranslational alteration. Phosphorylation is an important reversible change that controls protein activity, subcellular localization, complex formation, protein degradation, and so cell signalling networks. With all of these findings, it's believed that 30% to 65% of all proteins are phosphorylated, with some being phosphorylated numerous times. In comparison to expression analysis, phosphoproteomics adds two more levels of data. Because a change in phosphorylation status usually invariably reflects a change in protein activity, it provides indications as to which protein or pathway may be activated. While phosphoproteomics will substantially increase our understanding of the amount and types of phosphoproteins, its most promising use is the quick invest.. View More»
    DOI: 10.35248/ 0974-276X.22.15.577

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