GET THE APP

Rheumatology: Current Research

Rheumatology: Current Research
Open Access

ISSN: 2161-1149 (Printed)

+44-20-4587-4809

Mehta A

Department of Internal Medicine, Albert Einstein College of Medicine, Jacobi Medical Center, New York, USA

Publications
  • Mini Review   
    A Brief Review Highlighting the Broad Spectrum of Haemophagocytic Lymphohistiocytosis
    Author(s): Narvel H*, Mazzini J, Shao D, Mehta A, Kumar A and Yakkali S

    HLH is a rare, life-threatening condition characterized by an ineffective hyper stimulation of the immune system which leads to a pathologic rise in cytokine levels and to a hyper inflammatory state. Many conditions like Macrophage Activation Syndrome (MAS), sepsis, malignancies and even multi-inflammatory response syndrome after COVID 19 infection share overlapping clinical presentation and laboratory findings with HLH. Our review aims to provide updated clinical-practical generalities of HLH in terms of epidemiology, pathophysiology, clinical features, and management particularly in light of COVID19. The etiology of HLH can be classified as familial or secondary/ sporadic. The differentiation of primary and secondary HLH is very important because primary HLH may require different treatment modalities like hematopoietic stem cell transplantation. Since the emergence of the SARS-CoV2 .. View More»
    DOI: 10.35841/2161-1149.22.12.313

    Abstract HTML PDF

Top