ISSN: 2167-0250
Department of School of Medicine, University of Dundee, Scotland
 Research Article   
								
																A Systematic Review Focusing on the Use of Slo1 and Slo3 as Potential Targets for the Modulation of Sperm Motility and the Development of a Male Contraceptive Pill 
																Author(s): Maria Eleni Dionelli*             
								
																
						  Background: There is limited knowledge and research regarding male contraceptives. Surveys conducted by
  pharmaceutical companies have shown that males will not take a pill that will affect their hormones. However,
  data from a government survey conducted in the United Kingdom in 2019 showed that 33% of sexually active
  men agreed on taking a male contraceptive pill, which is the exact same percentage of women that currently use a
  hormonal contraception. This research project seeks to establish whether the stated evidence regarding Slo1 and
  Slo3 as potential targets is adequate, whether there is evidence of the expression of Slo1 and/or Slo3 cellular
  localization in human spermatozoa and whether it can lead to the development of a male contraceptive pill.
Methods: A systematic review on numerous databases was conducted. The sea.. View More»
						  
																DOI:
								10.35248/2167-0250.21.10.233