Immunotherapy: Open Access
Open Access

Department of Bionanoengineering, Hanyang University, Gyeonggi-do, 15588, Korea

Publications

• Short Communication   
  A Brief Note on Cytokine-Induced Killer Cells
  Author(s): Jong Wook*
  
  Cytokine-Induced killer (CIK) cells are raising growing interest in cellular antitumor therapy, as they can be easily expanded with a straightforward and inexpensive protocol, and are safe requiring only GMP-grade cytokines to obtain very high amounts of cytotoxic cells. CIK cells do not need antigen-specific stimuli to be activated and proliferate, as they recognize and destroy tumor cells in an HLA-independent fashion through the engagement of NKG2D. In several preclinical studies and clinical trials, CIK cells showed reduced allo reactivity compared to conventional T cells, even when challenged across HLA-barriers... View More»
  DOI: 10.35248/2471-9552.21.s1.003

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