Journal of Developing Drugs
Open Access

Department of Pharmacology, University of the West Indies, Kingston, Jamaica

Biography

Assistant Professor, Department of Computer Science & Engineering, I.K. Gujral Punjab Technical University, Bhikhiwind Campus (since June 2017).

Publications

• Research Article   
  Comparison of the Topical Analgesic Effects of a Novel Diclofenac Microemulsion to a Marketed Diclofenac Macroemulsion Formulation in Rats Using the Tail Flick Test
  Author(s): Tarique Benbow* and Jacqueline Campbell
  
  Current topical preparations do not provide optimal topical drug delivery. Microemulsions have been proposed to increase drug penetration across the skin, leading to increased bioavailability and efficacy of the drug product. This study compares the topical analgesic effects of novel diclofenac diethylamine (DDEA) water-in-oil (w/o) microemulsion to a marketed diclofenac diethylamine (DDEA) oil-in-water (o/w) macroemulsion (Voltaren Emulgel ®) in the treatment of acute thermal pain using the rat tail flick test. Eighteen (N=18) Sprague-Dawley rats were divided into three (3) groups (n=6). The groups were administered the novel microemulsion of DDEA (test group), the marketed macroemulsion of diclofenac (positive control group) and the microemulsion alone (negative control group); the rat tail flick test was performed after topical administration to ass.. View More»
  

  Abstract PDF