Journal of Medical Diagnostic Methods
Open Access
ISSN: 2168-9784
ISSN: 2168-9784
Laboratory of Microorganisms and Active Biomolecules, University Tunis El Manar, Tunisia
Research Article
Predictive Factors of Lymph Nodes Invasion and Factors Associated with Advanced Lymph Nodes Invasion in Gastric Cancer: Retrospective Study of 145 Cases
Author(s): Houyem Mansouri, Ines Zemni*, Ines Ben Safta, Mohamed Ali Ayadi, Tarek Ben Dhiab, Riadh Chargui and Khaled Rahal
Introduction: The detection of risk factors for lymph node extension in gastric cancers is crucial to standardize the
indications of endoscopic treatment in early tumors, to rationalize the extension of lymphadenectomy and to adapt
adjuvant and neoadjuvant therapies in locally advanced tumor. This study aimed to identify the clinical, biological,
and histological predictive factors of lymph node involvement in gastric cancer.
Patients and Methods: Clinical and histological data of 145 patients treated for gastric adenocarcinoma have been
enrolled. Univariate and multivariate analyzes of risk factors for lymph node involvement were performed.
Results: Lymph node invasion was found in 82.1% of cases. Among our patients, 32.4% were staged at pN3, 28.3% at
pN2, and 21.4% at pN1. In univariate analysis, lymph.. View More»