Journal of Hepatology and Gastrointestinal disorders
Open Access
ISSN: 2475-3181
+44-20-4587-4809
ISSN: 2475-3181
+44-20-4587-4809
Department of Human Reproduction, Grant Medical College, Mumbai, India
Review Article
An update on the Association of Gut-Liver Axis with Gut Micro biome Symbiosis Correlated NAFLD along with NAFLD- HCC with Potential Therapeutic Approaches: a Systematic Review
Author(s): Kulvinder Kochar Kaur*, Gautam Allahbadia and Mandeep Singh
Non-alcoholic Fatty Liver Disease (NAFLD) is believed to be amongst the maximum prevalent chronic liver disease globally secondary to pacey escalating obesity, Type 2 Diabetes Mellitus (T2DM), Metabolic Syndrome (MetS). In the form of a hepatic presentation of a metabolic disease NAFLD initiates with hepatic accrual along with propagationn towards hepatic inflammation; namely, Non-Alcoholic Steatohepatitis (NASH), hepatic fibrosis/ cirrhosis, with ultimate NAFLD associated Hepatocellular Carcinoma (NAFLD-HCC). Enhanced corroborate illustrated that gut microbiome possess an essential part in initiating besides propagatenag NAFLD via gut liver axis. The gut liver axis represents the reciprocal connection amongst gut as well as the liver constituted by the portal circulation, Bile Acids along with systemic circulation. This gut symbiosis aids in the generation of NAFLD by resulting in de.. View More»
DOI:
DOI: 10.35248/2475-3181.22.8.216