Journal of Hepatology and Gastrointestinal disorders
Open Access
ISSN: 2475-3181
ISSN: 2475-3181
Pathology Department, Mansoura School of Medicine, Mansoura University, Mansoura, Egypt
Research Article
Effect of Direct Acting Antiviral Drugs in Hepatitis C Virus infected Egyptian Patients with Nephropathy: A Single Center Study
Author(s): Alaa Sabry*, Ahmed Elsaeed, Shahera Eletreby, Fatma El-Husseini and Nagy Sayed Ahmed
Objectives: Determination of the sustained virologic response in chronic HCV infected patients with HCV related nephropathy receiving direct acting antiviral drugs and assessment of the immunological, clinical and renal responses to DAAs in this group of patients.
Methods: This prospective observational study was carried out over a period of two years and included 34 patients diagnosed with HCV nephropathy for whom virological, immunological, clinical and renal responses were assessed pre and 12 weeks post treatment who were planned to be treated with Direct Acting Antivirals (DAAs) (in the form of combination of OBV-PTV/r with RBV, combination of SOF/SIM, or combination of SOF/DCV with or without RBV according to the availability).
Results: Thirty four HCV nephropathy patients were observed while receiving DAAs an.. View More»
DOI:
10.35248/2475-3181.1000197