Andrology-Open Access
Open Access

Department of Medical Biochemistry, Baze University, Abuja, Nigeria

Publications

• Mini Review   
  Redefining Prostate Cancer Diagnosis: The Global Discourse on Single PSA Cut-Off Level in Diverse Populations
  Author(s): Edwin Nkemjika Okafor*, Ezra O Agbo, Innocent Okonkwo and Blessing Okpagu
  
  Controversy surrounds the use of Prostate Specific Antigen (PSA) as a definitive marker for identifying Prostate Cancer (PCa), despite its alarming incidence and mortality rates. This in-depth mini review examines recent published article and relevant literature analyzing the complex link between PCa and various risk factors. It also examines the potential of age-specific prostate-specific antigen reference intervals (ASRLs) as an alternative to a single PSA cutoff value. Our review uncovers that PCa is primarily rooted in advancing age and genetic predisposition (shared genes), with its impact further influenced by factors such as race, environmental conditions, lifestyle, and human development index. The existing studies suggest that ASRLs provide a viable alternative to overcome the limitations of relying on a single PSA cutoff value. Data from men belonging to different population.. View More»
  DOI: 10.35248/2167-0250.25.14.343

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