Medical & Surgical Urology
Open Access
ISSN: 2168-9857
ISSN: 2168-9857
Department of Biochemistry, University of Nigeria, Nsukka, Enugu State, Nigeria
Research Article
Evaluation of Hormonal and Biochemical Risk Factors for Benign Prostatic Hyperplasia: A Possible Way for Management and Prevention of Benign Prostatic Hyperplasia
Author(s): Chinedum Joseph Ndefo, Parker Elijah Joshua* and Eleazar Chukwuemeka Anorue
Objective: To identify some risk factors that contributes to the development and severity of BPH among the elderly
in Enugu state, Nigeria.
Study design: One hundred men aged 53 years-85 years were used for the study; the study was divided into two
groups consisting of 50 male patients diagnosed with BPH and 50 healthy subjects.
Methods: Twenty millilitre of whole blood samples were collected from each patient and the following parameters
were investigated; oestrogen, testosterone, lipid profile, PSA, PAP, TAP, electrolyte concentration and antioxidant
biomarkers.
Results: It was found that increase in PAP, TAP, total cholesterol, TAG, LDL, oestrogen, potassium and sodium and
decrease in levels of catalase, GPx, selenium, HDL and testosterone are risk factors for the d.. View More»
DOI:
10.35248/2168-9857.23.12.324