Immunogenetics: Open Access

Immunogenetics: Open Access
Open Access

+44 1223 790975

Dongbing Zhao

Department of Pancreatic and Gastric Surgery, National Clinical Research Center for Cancer, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

  • Research Article   
    Diagnostic Value of Circulating Nucleic Acids in Gastric Cancer: A Systematic Review
    Author(s): Xiaojie Zhang, Hong Zhou, Tongbo Wang, Chaorui Wu and Dongbing Zhao*

    Background: At present, the diagnosis of gastric cancer lacks sufficient biomarkers. In this review, we will identify and discuss the value of circulating free nucleic acids in the diagnosis of gastric cancer, in order to find a way to sort out the diagnostic markers for gastric cancer. Methods: A systematic search was performed on PubMed using the following keywords: (gastric cancer) and (blood or plasma or serum) and (biomarker) and (DNA or RNA or cfDNA or cell-free DNA or RNA or CTC). and the supplementary materials were added from Embase The Science Citation Index and The Cochrane. All the studies contain biomarkers based on CTCs, DNAs, RNAs were reviewed and of which include sensitivity, specificity, and/or AUC/ROC values were further discussed. Results: 458 studies were searched and 87 contain.. View More»
    DOI: 10.35248/igoa.20.5.125

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