Chemotherapy: Open Access
Open Access
ISSN: 2167-7700
ISSN: 2167-7700
Department of Psychology, Holy Spirit University of Kaslik, Jounieh, Lebanon
Research Article
Response Evaluation to Oxaliplatin-Based Adjuvant Chemotherapy after Curative Resection between Right and Left-Sided Stage II and III Colon Cancer: A Retrospective Survival Analysis
Author(s): Cynthia Eid Nasr*, Cassandra Nasr, Stephanie El Hawat, Christelle El Riachy and Marcel Antoine Massoud
Background: Colon cancer is divided into right and left colon cancer. It manifests with distinct physiopathology, histology, presentation, and prognosis. The choice of treatment for stage IV disease is based on tumor sidedness. However, until now, stage II and III diseases are being treated with the same regimens regardless of the tumor location.
Methods: A retrospective survival analysis was performed between January 1, 2009 and December 31, 2019 on 57 Lebanese patients who were diagnosed with stage II or III colon cancer and who underwent curative surgical resection followed by Oxaliplatin-based adjuvant chemotherapy (XELOX or FOLFOX). Response to chemotherapy, as well as recurrence, were assessed with thoraco-abdominopelvic CT scan or Magnetic Resonance Imaging (MRI), scheduled regularly.
Results: Left-sided tum.. View More»