Internal Medicine: Open Access

Internal Medicine: Open Access
Open Access

ISSN: 2165-8048

+44 1300 500008

Cosmin Constantin Oprea

Independent Research, Bucharest, Romania

  • Research Article   
    Potential Approach of Hepatitis B by Inhibiting MDSC to Obtain Control of the Immune System
    Author(s): Cosmin Constantin Oprea*

    Purpose of Review: Hepatitis B virus infection and the immune response in babies and adults. Findings: The presence of myeloid-derived suppressor cells (MDSCs) in new-borns makes Hepatitis B to become chronic over years with both antigens present in the blood, HBs and HBe, the immune system not being able to recognize the infection in the first years of life. The expansion of myeloid-derived suppressor cells (MDSCs) allows the immune system to maintain the infection with Hepatitis B, although the patient reaches adult age, because myeloidderived suppressor cells (MDSCs) are responsible for the disfunction of the immune system and not the virus itself. Our goal is to show what is maintaining T cell exhaustion in hepatitis B, why this is happening and what is responsible for this. MDSC is responsible for chronic Hepatitis B infection.. View More»
    DOI: 10.35248/2165-8048.21.s6.001

    Abstract HTML