Journal of Cell Science & Therapy

Journal of Cell Science & Therapy
Open Access

ISSN: 2157-7013

Asuka Takeishi

RIKEN Center for Brain Science (CBS), Wako, Japan

  • Review Article   
    Insulin Signaling Acts Extensively in C. elegans Starvation-Associated Learning and Behavioral Plasticity
    Author(s): Kristina N Galatsis and Asuka Takeishi*

    Behavioral plasticity is one of the most important strategies by which animals can adapt to transient environmental changes for their survival. Biological systems must be flexible enough to induce and maintain behavioral plasticity while still being finely regulated, especially in response to life-threatening situations like starvation. Animals produce behavior in response to stimuli, which can be altered when starvation is paired with a range of stimuli (associative learning). Such mechanisms of associative learning have been studied extensively in C. elegans. Use of C. elegans provides an ideal system to study the neural mechanisms of integration of external cues with internal state for multiple reasons. First, C. elegans is one of few organisms for which the complete, stereotyped connectome of neurons is available. This allows researc.. View More»
    DOI: 10.35248/2157-7013.21.s5.315

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