Andrology-Open Access
Open Access
ISSN: 2167-0250
ISSN: 2167-0250
Indian Council of Agricultural Research-Central Sheep and Wool Research Institute, Bikaner, Rajasthan, India
Commentary
Melatonin and Canthaxanthin Ameliorate Oxidative Stress and Improve Semen Quality: A Special Reference to Ram
Author(s): Ashok Kumar*, Shivendra Kumar Bhalothia, Thirumala Rao Talluri, SS Dangi, Arun Kumar Tomar, AK Patel, Nirmala Saini, Manish Kanwat and Tapendra Kumar
Success in the outcomes of applied assisted reproductive techniques mainly relies on the quality of the semen. Oxidative stress created by Reactive Oxygen Species (ROS) and Lipid Peroxidation (LPO) generated during different steps of semen preservation reduces semen quality. Melatonin and canthaxanthin are potent antioxidants involved in many biological processes. They have excellent capacity to scavenge free radicals, combat against oxidative stress and improve endogenous antioxidant defenses. Melatonin is well established antioxidant in semen preservation to protect against oxidative stress-induced damage; however, little literature is available on use of canthaxanthin as semen extender additive. Melatonin and its metabolites act as direct or indirect scavenger of free radicals arrest LPO and reduce generation of ROS, hence oxidative stress, thereby shielding seminal quality to prol.. View More»
DOI:
10.35248/2167-0250.22.11.266