Rheumatology: Current Research

Rheumatology: Current Research
Open Access

ISSN: 2161-1149 (Printed)


Ankit Kumar

Institute of Bioinformatics, Bangalore, India

  • Case Report   
    A Rare Disease with its Uncommon Presentation- Antisynthetase Syndrome Presenting as Unexplained Fever
    Author(s): Ankit Kumar*

    Anti-Synthetase Syndrome (ASS) is a rare autoimmune disorder characterized by Interstitial Lung Disease (ILD), inflammatory myositis, fever, Raynaud’s phenomenon, mechanic hand, and inflammatory polyarthritis in the setting of antibodies against amino acyl-transfer RNA synthetases, with anti-Jo-1 antibody being the most common. This diagnosis should always come to mind in patients that present with signs of myositis, dermatomyositis, or polymyositis associated with interstitial lung disease. In this paper, we report a rare case of pyrexia of unknown origin in a 25-year-old man who presented with a 01-month history of fever, symmetrical polyarthralgia, myalgia, weight loss of 3 kg, and progressive muscle weakness associated with dyspnoea. Initially evaluation for fever was negative. Further tests revealed raised acute phase reactant, positive ANA with Cytoplasmic pattern, positiv.. View More»
    DOI: 10.35248/2161-1149.21.s16.002

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