Biochemistry & Pharmacology: Open Access
Open Access
ISSN: 2167-0501
+44-20-4587-4809
ISSN: 2167-0501
+44-20-4587-4809
Yousef Rezaei Chianeh
Kasturba Medical College,
Manipal, 576104, Karnataka
India
Research Article
Hepatoprotective and Renoprotective Potentials of the Aqueous Extract of Bixa orellana on Streptozotocin Induced Diabetic Rats
Author(s): Vinutha R Bhat, Yousef Rezaei Chianeh, Padmanabha Udupa, Anushree U and Samreen SheikhVinutha R Bhat, Yousef Rezaei Chianeh, Padmanabha Udupa, Anushree U and Samreen Sheikh
Objective: The present study was undertaken to evaluate the effects of the aqueous extract of Bixa orellana on the liver enzymes such as AST, ALT and ALP and also to evaluate the efficacy of the extract for the protection of the renal function in streptozotocin induced diabetic rats.
Methods: Diabetes was induced by administering streptozotocin dissolved in saline while the normal control group was given propylene glycol. Diabetes induced animals were randomly assigned into different groups. Blood samples were collected from all the control and experimental group. Estimation of urea, uric acid and creatinine as well as the liver enzymes such as AST, ALT and ALP were assayed. These estimations were carried out on day 30 only.
Results: The 30 days treatment with the aqueous extract (200 mg/kg body weight) showed no statist.. View More»
DOI:
10.4172/2167-0501.1000255