Endocrinology & Metabolic Syndrome
Open Access
ISSN: 2161-1017
+44 1478 350008
ISSN: 2161-1017
+44 1478 350008
Vargas U Hernando
University of Cauca Popayán-Cauca, Hospital Universitario San José,
Carrera 6 No 10N-142 3er piso, Colombia
Tanzania
Review Article
Role of Thyroid Hormones in Different Aspects of Cardiovascular System
Author(s): Vargas U HernandoVargas U Hernando
Besides its metabolic and thermoregulatory tissue effects, thyroid hormones plays a fundamental role in the cardiovascular homeostasis, mediated by genomic and non-genomic effects. Consequently, thyroid hormones deficits, as well as excesses, are expected to result in profound changes in cardiac function regulation and cardiovascular hemodynamics. Hyperthyroidism induces a hyperdynamic cardiovascular state, which is associated with enhanced left ventricular systolic, diastolic function, and the chronotropic and inotropic properties of thyroid hormones. On the other hand; in a hypothyroid state, thyroid hormones deficiency results in lower heart rate and weakening of myocardial contraction and relaxation, with prolonged systolic and early diastolic times. Subclinical hypothyroidism is characterized by abnormal lipid metabolism and cardiac dysfunction; diastolic hypertension conferring an .. View More»
DOI:
10.4172/2161-1017.1000166