Journal of Hepatology and Gastrointestinal disorders
Open Access
ISSN: 2475-3181
+44-20-4587-4809
ISSN: 2475-3181
+44-20-4587-4809
Testa Anna
University “Federico II” of Naples,
Via S. Pansini 5, 80131, Naples
Italy
Case Report
Nodular Regenerative Hyperplasia: A Rare Complication of
Treatment with Thiopurines in Patients with Crohn’s Disease
Author(s): Testa Anna, Terracciano Luigi, D’Armiento Maria Rosaria, Imperatore Nicola, Nardone Olga Maria, Rispo Antonio and Castiglione FabianaTesta Anna, Terracciano Luigi, D’Armiento Maria Rosaria, Imperatore Nicola, Nardone Olga Maria, Rispo Antonio and Castiglione Fabiana
A 25-year-old male with ileal pre-anastomotic recurrence of Crohn's disease (CD) experienced nodular regenerative hyperplasia (NRH) secondary to treatment with azathioprine (AZA). The subject showed increase in cholestasis indices and a reduction in platelets. The diagnosis of NRH was established by liver biopsy; outcome was favourable after treatment discontinuation, with complete normalization of liver function tests within less than one year... View More»
DOI:
10.4172/2475-3181.1000162