Gynecology & Obstetrics
Open Access
ISSN: 2161-0932
ISSN: 2161-0932
Shylesh S. Bhaskaran
Tanzania
Editorial
Progestins/Antiprogestins: Role in Pathogenesis and Treatment for Endometriosis
Author(s): Shylesh S. Bhaskaran and Hareesh B. NairShylesh S. Bhaskaran and Hareesh B. Nair
Endometriosis is a painful gynecological condition in the fertile-age in which presence of endometrial tissue develops outside the uterus, which under normal situation found only in the inside lining of the uterus, attach to pelvic floor, endometrium or peritoneal cavity. Endometriosis cause abdominal pain, bleeding, irregular menstrual cycles with excessive pain, inflammatory responses and infertility. Retrogressive menstruation and invasion theories have been well studied in the pathogenesis of endometriosis. Role of steroids including estrogen, gonadotropin releasing hormones has been documented and major treatment strategies are based on steroid biology of endometriosis. Current treatment strategies are less successful and solely focusing on the late phase of the disease. The exact role of progesterone in the initiation (initial phase) of endometriosis has not been well studied or.. View More»
DOI:
10.4172/2161-0932.1000e105