Gynecology & Obstetrics
Open Access
ISSN: 2161-0932
ISSN: 2161-0932
Shuchi Jain
India
Research Article
Maternal Vitamin D Deficiency: A Risk Factor for Gestational Diabetes Mellitus in North India
Author(s): Madhu Jain, Sweety Kapry, Shuchi Jain, SK Singh and TB SinghMadhu Jain, Sweety Kapry, Shuchi Jain, SK Singh and TB Singh
Objective: The aim was to assess maternal vitamin D deficiency in early pregnancy and subsequent risk of developing gestational diabetes mellitus (GDM) in north India.
Methods: Nested case control study was done taking 550 antenatal women. Two maternal blood samples, one at <20 wks and the other at term along with cord blood were taken. Vitamin D was estimated by 25-Hydroxyvitamin D 125 I RIA Kit and categorised according to ACOG (2011) criteria. Patients were categorised into GDM and control groups as per ADA recommendations. Pearson χ2, ANOVA, linear correlation and logistic regression were used for statistical analysis.
Results: High prevalence (72.8%) of vitamin D deficiency was found in early pregnancy. Serum 25(OH) D concentrations were significantly lower (46% less) in women who subsequently developed GD.. View More»
DOI:
10.4172/2161-0932.1000264