Surgery: Current Research

ISSN - 2161-1076

Shahzeer Karmali

Shahzeer Karmali

Room 405, CSC 10240 Kingsway Avenue, Edmonton, Alberta
Canada

Publications
  • Review Article
    Colorectal Adenocarcinoma and Inflammatory Bowel Disease: An Update and Review
    Author(s): Michael Laffin and Shahzeer KarmaliMichael Laffin and Shahzeer Karmali

    Inflammatory bowel disease and its two prototypic illnesses: Crohn’s disease and ulcerative colitis have long been thought to confer an increased risk of colorectal cancer, although the magnitude of this effect has been difficult to elucidate. The driving factors behind this relationship include genetics, microbial disturbances, alongside molecular and inflammatory misregulation. The epidemiologic understanding of the inflammatory bowel disease-colorectal cancer relationship has evolved over the last decade. This review will focus on the epidemiology of colorectal cancer in inflammatory bowel disease, and detail the elements driving disease development. Patient risk factors, many that increase the intensity or duration of inflammation, will be detailed. Finally, a practical approach to the tools that clinicians have at their disposal in preventing th.. View More»

    DOI: 10.4172/2161-1076.1000249

    Abstract PDF

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