Gynecology & Obstetrics
Open Access

Sadhana Joshi

Publications

• Review Article
  A Novel Molecular Mechanistic Hypothesis to Validate the Therapeutic Effects of Tribulus terrestris (Gokshur) to Ameliorate Pathophysiology and Improve Pregnancy and Fetal Outcome in Preeclampsia
  Author(s): Anitha Kilari, Manasi Deshpande and Sadhana Joshi Anitha Kilari, Manasi Deshpande and Sadhana Joshi
  
  Preeclampsia is a pregnancy hypertensive disorder which leads to both maternal and fetal morbidity and mortality. Evidences suggest that factors such as maternal micronutrients and oxidative stress are involved in the pathology of preeclampsia. Studies on preeclampsia and preterm have shown altered maternal micronutrients (folic acid, vitamin B12) and their probable epigenetic mechanisms leading to metabolic and neurobehavioral disorders in the offspring in later life. Our earlier study has also shown increased oxidative stress and reduced birth outcome in preeclampsia. Reports also suggest that micronutrients deficiency is prevalent in Indian women leading to oxidative stress and adverse pregnancy outcomes. However, studies on supplementation with micronutrients/synthetic antioxidants have shown controversial results in preeclampsia. Further, there are no reports on supplementation w.. View More»
  DOI: 10.4172/2161-0932.1000195

  Abstract PDF

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