Anatomy & Physiology: Current Research
Open Access
ISSN: 2161-0940
+44 1300 500008
ISSN: 2161-0940
+44 1300 500008
Odigie OM
Faculty of Basic Medical Sciences, College of Health Sciences,
Abraka, Delta State
Nigeria
Research Article
Hepatic, Pancreatic, and Renal Histo-Morphologic Alterations in Administration of Aqueous and Ethanol Seed Extract of Buchholzia Coriacea in Alloxan-Induced Diabetic Rats
Author(s): Gbagbeke KO, Odigie OM and Naiho AOGbagbeke KO, Odigie OM and Naiho AO
Physiologically, Insulin is a hormone that helps the body’s cells to absorb glucose (sugar) so it can be used as a source of energy. In diabetics however, due to pancreatic production of insufficient amounts of insulin or failure of body’s cells to respond to available insulin, blood and urine glucose levels build up to cause excessive urination, thirst, hunger, and problems with fat and protein break down. Recently, medicinal herbs have been implicated in traditional medical practice for the treatment of this ailment (Diabetes Mellitus, DM). Present study sought to investigate the effect(s) of oral administration of aqueous and ethanol extracts of Buchholzia Coriacea on the liver, pancreas and kidney in normal and alloxan-induced diabetic rats. Forty adult rats of both sexes were randomly assigned into two groups (normoglycemic and hyperglycemic). While group 1 (.. View More»
DOI:
10.4172/2161-0940.1000295