Gynecology & Obstetrics

Gynecology & Obstetrics
Open Access

ISSN: 2161-0932

Mustapha AO

Mustapha AO

Nigeria

Publications
  • Research Article
    Comparison of Intramuscular Magnesium Sulphate with Low Dose Intravenous Regimen in the Management of Eclampsia in Low Resource Setting: A Randomised Study

    Author(s): Idowu A, Adekanle DA, Loto OM, Ajenifuja KO, Badejoko OO, Tijani Am and Mustapha AO Idowu A, Adekanle DA, Loto OM, Ajenifuja KO, Badejoko OO, Tijani Am and Mustapha AO

    Background: Eclampsia is a major cause of maternal and perinatal morbidity and mortality. Magnesium sulphate is currently the gold standard in the management of eclamptic fit. As a result of its toxicity, current efforts are being geared towards discovering a lower dosage without compromising its efficacy. Objective: To compare the effectiveness of low-dose magnesium sulphate and standard Pritchard regimen in controlling eclamptic fit and preventing adverse maternal and neonatal outcomes in eclamptic patients Methodology: This study was a randomized clinical trial comparing low-dose with standard Pritchard regimen. Twenty eight patients (the cases) randomized into low-dose regimen group received 4g loading dose, I.V. 4 g and a maintenance dose of 0.6 g/hr through intravenous infusion for a period of 24 hours post-d.. View More»
    DOI: 10.4172/2161-0932.1000249

    Abstract

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