Gynecology & Obstetrics
Open Access
ISSN: 2161-0932
ISSN: 2161-0932
Marina Knauf
Germany
Research Article
Effectiveness and Tolerability of a Synbiotic Vaginal Suppository for the Treatment of Bacterial Vaginosis
Author(s): Andreas Schwiertz, Marina Knauf, Ute Pohl, Brunhilde Hackel and Hans-Jorg MuellerAndreas Schwiertz, Marina Knauf, Ute Pohl, Brunhilde Hackel and Hans-Jorg Mueller
Objective: Aim of this clinical study was the evaluation of the medical device SymbioVag® on bacterial vaginosis (BV) and its tolerability Method: An open-label study was conducted on 103 female subjects aged 18 to 56 years with manifested BV. Enrolled subjects were treated for 10 successive days with the synbiotic vaginal suppository SymbioVag® containing Lactobacillus acidophilus, Lactobacillus gasseri in combination with the prebiotic substance inulin BV was diagnosed using the Amsel criteria. In addition, bacterial counts of lactobacilli, Gardnerella vaginalis, Atopobium vaginae and total anaerobes were detected. Symptoms associated with bacterial vaginosis were rated by the patients before and after the use of SymbioVag® Results: Treatment with SymbioVag® reduced vaginal pH in more than 80% of the .. View More»
DOI:
10.4172/2161-0932.1000275