Biochemistry & Pharmacology: Open Access
Open Access

Lionella Palego

Publications

• Review Article
  Sulfur Metabolism and Sulfur-Containing Amino Acids Derivatives – Part II: Autism Spectrum Disorders, Schizophrenia and Fibromyalgia
  Author(s): Lionella Palego, Laura Betti and Gino Giannaccini Lionella Palego, Laura Betti and Gino Giannaccini
  
  The metabolism of sulfur (S) compounds concurs to the maintain of cell homeostasis and tissue integrity in the human body. Sulfur chemical species act in all cells as anti-oxidant/scavenging agents or regulators of membrane stability/excitability. At the same time, they also exert tissue-dependent functions behaving as protective molecules of the liver and cardiovascular system, as modulators of the immune response, gut activity and CNS neurotransmitter signaling. The involvement of S compounds in human complex, chronic, disabling diseases at multifaceted pathogenesis is actually under investigation: altered levels of S metabolites could be in fact bio-indicators of impaired oxidation state in the body and their unbalance could be risk factors for disease onset. By the present review, we will discuss data from the literature which unearth an altered S biochemistry in human complex ill.. View More»
  DOI: 10.4172/2167-0501.1000159

  Abstract PDF

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