Biochemistry & Pharmacology: Open Access
Open Access
ISSN: 2167-0501
ISSN: 2167-0501
Lionella Palego
Department of Clinical and Experimental Medicine, via Savi 10,
Italy
Review Article
Sulfur Metabolism and Sulfur-Containing Amino Acids Derivatives – Part II: Autism Spectrum Disorders, Schizophrenia and Fibromyalgia
Author(s): Lionella Palego, Laura Betti and Gino GiannacciniLionella Palego, Laura Betti and Gino Giannaccini
The metabolism of sulfur (S) compounds concurs to the maintain of cell homeostasis and tissue integrity in the human body. Sulfur chemical species act in all cells as anti-oxidant/scavenging agents or regulators of membrane stability/excitability. At the same time, they also exert tissue-dependent functions behaving as protective molecules of the liver and cardiovascular system, as modulators of the immune response, gut activity and CNS neurotransmitter signaling. The involvement of S compounds in human complex, chronic, disabling diseases at multifaceted pathogenesis is actually under investigation: altered levels of S metabolites could be in fact bio-indicators of impaired oxidation state in the body and their unbalance could be risk factors for disease onset. By the present review, we will discuss data from the literature which unearth an altered S biochemistry in human complex ill.. View More»
DOI:
10.4172/2167-0501.1000159