Biochemistry & Pharmacology: Open Access
Open Access
ISSN: 2167-0501
+44-20-4587-4809
ISSN: 2167-0501
+44-20-4587-4809
Laurence Dubrez
Université de Bourgogne Franche-Comté,
LNC UMR1231, 21000 Dijon
France
Mini Review
SMAC Mimetics: Promising Therapeutic Agents in Cancer and other Diseases
Author(s): Laurence DubrezLaurence Dubrez
Smac mimetics are a very promising new class of anticancer agents demonstrating an acceptable safety profile and efficacy in some preclinical models of cancers when used as a single agent or in combination with conventional or nonconventional therapies. Future preclinical and clinical trials could enlarge their spectral of action in inflammatory, fibrotic and infectious diseases.
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DOI:
10.4172/2167-0501.1000244