Biochemistry & Pharmacology: Open Access
Open Access
ISSN: 2167-0501
ISSN: 2167-0501
Karunakar Shukla
India
Review Article
Biosurfactants: A New Pharmaceutical Additive for Solubility Enhancement and Pharmaceutical Development
Author(s): Sandeep Singh Bhadoriya, Narendra Madoriya, Karunakar Shukla and Parihar MSSandeep Singh Bhadoriya, Narendra Madoriya, Karunakar Shukla and Parihar MS
Biosurfactants are structurally diverse group of surface-active substances produced by microorganisms. At present, biosurfactants have gained importance in the pharmaceutical, biomedical, cosmetic and food industry, with a high added value, are still developing. Surfactants have numerous uses in pharmaceuticals, for solubilization of hydrophobic drugs in aqueous media, as components of emulsion or surfactant self-assembly vehicles for oral and transdermal drug delivery, as plasticizers in semisolid delivery systems, and agents to improve drug absorption and as penetration enhancer. Many pharmaceuticalgrade surfactants consist of saccharide- or polyol-fatty acid esters or fatty alcohol ethers that are biosurfactant. This article describes classical and new biosurfactants’ producing bacteria along with their significant role as pharmaceutical additives in development of pharmaceut.. View More»
DOI:
10.4172/2167-0501.1000113