Gynecology & Obstetrics
Open Access
ISSN: 2161-0932
ISSN: 2161-0932
Karim HI Abd-El-Maeboud
Egypt
Research Article
Endometrial Nerve Fibers Detection in Women with Different Gynecological Pathologies: A Cross Sectional Study
Author(s): Ahmed EH Elbohoty, Karim HI Abd-El-Maeboud, Nashwa Elsaid, Reda Mokhatar, Walid E Mohammed, Hosam M Hemeda, Tamer A El-Refaee, Mahmoud A El-Shourbagy, Nahla M Awad, Magda M Abd-Elsalam, Abdellatif G Elkholy and Ahmad AlanwarAhmed EH Elbohoty, Karim HI Abd-El-Maeboud, Nashwa Elsaid, Reda Mokhatar, Walid E Mohammed, Hosam M Hemeda, Tamer A El-Refaee, Mahmoud A El-Shourbagy, Nahla M Awad, Magda M Abd-Elsalam, Abdellatif G Elkholy and Ahmad Alanwar
Objective: To show the existence and density of endometrial nerve fibers in endometriosis and other gynecological pathologies and their relation to pain.
Methods: This cross-sectional study involved 325 women planned to have gynecologic surgeries at Ain Shams University Maternity Hospital from December 2010 to February 2014. The diagnosis was adenomyosis, uterine fibroid, endometrial hyperplasia or carcinoma, polycystic ovarian syndrome (PCOS), ovarian tumors and endometriosis. Endometrial tissue was obtained during hysterectomy or with a curette and then immunostained with the pan neuronal marker anti PGP 9.5 to detect the endometrial nerve fibers and to quantify their density if present.
Results: Endometrial nerve fibers were detected in all cases of endometriosis and 13.7% of other pathologies except PCOS (p<0.001).. View More»
DOI:
10.4172/2161-0932.1000418