Biochemistry & Pharmacology: Open Access
Open Access

Jihong Yang

Publications

• Research Article
  Morbidity of Diabetes Mellitus in Cynomolgus Monkeys
  Author(s): Saimei Yan, Ting Wang, Changhong Zhang, Peng Wang, Xiangting Xu, Jihong Yang and Cui YangSaimei Yan, Ting Wang, Changhong Zhang, Peng Wang, Xiangting Xu, Jihong Yang and Cui Yang
  
  Object: To determine the morbidity of diabetes mellitus in cynomolgus monkey by performing the Oral Glucose Tolerance Test (OGTT). Method: OGTTs were performed in 600 male cynomolgus monkeys, aging 4-18 years. The values of plasma glucose (PG) and insulin (Ins) were detected. Result: Significant differences were found in the values of PG and Ins among groups with different ages. The values of PG of 4 pathological courses of DM were: Normal glucose tolerance (NGT) group: Fasting plasma glucose (FPG) < 6.10 mmol/L and 2hPG < 7.8 mmol/L; Impaired fasting glucose (IFG) group: 6.10 mmol/L ≤ FPG < 7.0 mmol/L and 2hPG < 7.8 mmol/L; Impaired glucose tolerance (IGT) group: FPG < 7.0 mmol/L and 7.8 mmol/L ≤ 2hPG < 11.1 mmol/L; diabetes mellitus (DM) group: FPG ≥ 7.0 mmol/L or 2hPG ≥ 11.1 mmol/L. The morbidity of diabetes mellitus in the tested cynomol.. View More»
  DOI: 10.4172/2167-0501.1000163

  Abstract PDF

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