Gynecology & Obstetrics
Open Access
ISSN: 2161-0932
ISSN: 2161-0932
Ibrahim Karaca
Turkey
Research Article
Treatment of Premenstrual Syndrome with Progesterone in Women with Polycystic Ovary Syndrome
Author(s): Ibrahim Karaca, Sefa Kurt, Emrah Toz, Mehmet Adiyeke and Mehmet Tunç CandaIbrahim Karaca, Sefa Kurt, Emrah Toz, Mehmet Adiyeke and Mehmet Tunç Canda
Introduction: Premenstrual Syndrome (PMS) is defined as a group of disorders characterized by emotional and physical symptoms that occur in the luteal phase of the menstrual cycle and subside following menstruation. The reported prevalence of severe PMS is variable between 3% and 24%. Etiology of PMS remains unknown but cyclical ovarian activity and the effect of estradiol and progesterone on the neurotransmitters serotonin and gammaaminobutyric acid appear to be key factors. One hypothesis that the cause of PMS is the deficiency of progesterone and its derivatives. Polycystic Ovary Syndrome (PCOS) is characterized with chronic anovulation and oligo-ovulation. Due to this there is a distinct deficiency of progesterone and its derivatives in PCOS. The aim of this study was to investigate the efficiency of progesterone therapy for PMS in woman with PCOS. M.. View More»
DOI:
10.4172/2161-0932.1000151