Gynecology & Obstetrics

Gynecology & Obstetrics
Open Access

ISSN: 2161-0932

Hareesh B. Nair

Hareesh B. Nair
Southwest National Primate Research Center, Texas Biomedical Research Institute,
7620 NW Loop 410, San Antonio TX 78227

  • Editorial
    Progestins/Antiprogestins: Role in Pathogenesis and Treatment for Endometriosis
    Author(s): Shylesh S. Bhaskaran and Hareesh B. NairShylesh S. Bhaskaran and Hareesh B. Nair

    Endometriosis is a painful gynecological condition in the fertile-age in which presence of endometrial tissue develops outside the uterus, which under normal situation found only in the inside lining of the uterus, attach to pelvic floor, endometrium or peritoneal cavity. Endometriosis cause abdominal pain, bleeding, irregular menstrual cycles with excessive pain, inflammatory responses and infertility. Retrogressive menstruation and invasion theories have been well studied in the pathogenesis of endometriosis. Role of steroids including estrogen, gonadotropin releasing hormones has been documented and major treatment strategies are based on steroid biology of endometriosis. Current treatment strategies are less successful and solely focusing on the late phase of the disease. The exact role of progesterone in the initiation (initial phase) of endometriosis has not been well studied or.. View More»
    DOI: 10.4172/2161-0932.1000e105

    Abstract PDF

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