Endocrinology & Metabolic Syndrome
Open Access
ISSN: 2161-1017
+44 1478 350008
ISSN: 2161-1017
+44 1478 350008
Fritz-Line Vélayoudom-Céphise
University Hospital of Pointe-à-Pitre,
Guadeloupe
France
Research Article
Relationship between Testosterone and Sex Hormone Binding Globulin Concentrations with Cardiometabolic Parameters and Macrovascular Disease in Afro-Caribbean Men with Type 2 Diabetes
Author(s): Fritz-Line Vélayoudom-Céphise, Lydia Foucan, Laurent Larifla, Vanéva Chingan, Jacqueline Bangou, Catherine Massard, Christophe Armand, Jacqueline Deloumeaux and Fabrice BonnetFritz-Line Vélayoudom-Céphise, Lydia Foucan, Laurent Larifla, Vanéva Chingan, Jacqueline Bangou, Catherine Massard, Christophe Armand, Jacqueline Deloumeaux and Fabrice Bonnet
Introduction: Low testosterone concentrations have been reported in type 2 diabetes (T2D) and Coronary Artery Disease (CAD). Contrary to diabetes, the prevalence of CAD is lower in Afro-Caribbean (AC) from French West Indies islands than in people from mainland France. However, CAD is a frequent complication of T2D. To evaluate this paradoxical situation, we investigated the prevalence of sex steroids deficiency that might be associated with CAD in AC men with T2D and the relationships with metabolic parameters.
Methods: We performed a cross-sectional study in the Department of Diabetology of the University Hospital of Guadeloupe. Clinical and biological data were collected from men with T2D. Total Testosterone (TT) and Sex Hormone Binding Globulin (SHBG) concentrations were measured using electrochemiluminescence and immunoradiometric assay.. View More»
DOI:
10.4172/2161-1017.1000162