Gynecology & Obstetrics
Open Access
ISSN: 2161-0932
ISSN: 2161-0932
Frhana Rahmat
Universiti Pertahanan Nasional,
Sungai Besi, Kuala Lumpur
Malaysia
Research Article
Immunohistochemical Expression of Human Epididymis 4 (He4) in Ovarian Serous Carcinoma in Hospital Serdang from the Year 2006- 2013
Author(s): Frhana Rahmat and Hairuszah IthninFrhana Rahmat and Hairuszah Ithnin
Ovarian cancer is the fifth most common cause of cancer death in women worldwide and is the fourth leading cause of cancer related deaths in Malaysia. Ovarian cancer are classified based on histological types, because it is an important surrogate for genetic, prognostic, and predictive information about response to treatment. The malignant epithelial tumor, that is ovarian carcinoma (OC) is the most common group and the four most common subtypes of OC are serous, endometrioid, clear cell and mucinous. Among the OC, ovarian serous carcinoma (OSC) is the most common subtypes. Most of the women with OC presented with locally advanced disease or distant metastasized at the time of diagnosis. The two-tier grading system (also known as MDACC [M.D Anderson Cancer Center] grading system) has been accepted worldwide. Human epididymis 4 (HE4) is a new protein which is frequently overexpressed i.. View More»
DOI:
10.4172/2161-0932.1000453