Biochemistry & Pharmacology: Open Access
Open Access
ISSN: 2167-0501
+44-20-4587-4809
ISSN: 2167-0501
+44-20-4587-4809
Fan Zhiyong
Engineering Research Center for Feed Safety and Efficient Utilization of Ministry of Education, Institute of Animal Nutrition,
Hunan, 410128
China
Research Article
Effects of Passive Immunization against Peptide Tyrosine Tyrosine on the Activity of Digestive Enzymes in Rats
Author(s): Fan Zhiyong, Zhang Guanglei, Zhou Dinggang, Liang Zhe, Wu Xin and Wang FenglaiFan Zhiyong, Zhang Guanglei, Zhou Dinggang, Liang Zhe, Wu Xin and Wang Fenglai
The object of this study was to investigate the effect of serum antibody of peptide tyrosine tyrosine on activities of digestive enzymes in rats. A total of sixty sprague-dawley (SD) rats weighing 87.77 ± 1.61 g were randomly allocated to 1 of 4 dose treatment:0 (control), 50 μL, 100 μL, or 200 μL peptide tyrosine tyrosine antiserum during the 21-d experimental period. The activity of amylases and lipases in the pancreas and duodenum as well as gastric pepsin was measured at the end of the study. The results showed that the activity of lipases in the pancreas and duodenum increased with increasing peptide tyrosine tyrosine antiserum level, but obvious tendency of pancreatic lipases activity between all treatments was not observed(P>0.05). The lipase activity in the duodenum showed a significant increase (P<0.05) in the groups treated .. View More»
DOI:
10.4172/2167-0501.1000188